yup i did the patch.. as i said above..You did read this, right?
http://www.isxgames.com/forums/showthread.php?t=2362
Then, I'm not sure what to tell you ...if you apply that patch above without innerspace being in your registry, then it will not install properly.
So, you might want to make sure that innerspace is properly installed on your computer (ie, don't just copy it over..make sure it's INSTALLED.)
My suggestion is to close Vanguard, uninstall ISXVG, uninstall InnerSpace ..then go and redownload/reinstall InnerSpace and then ISXVG. If everything is installed properly, it WILL work.