All MMO's have that mind-numbing "grind", and Eve is no exception. We grind agent missions, and we grind minerals.
IsxEve, like other ISX modules that preceeded it, allows you to write scripts for the mind-numbing elements of the game, while you concentrate on the fun elements of the game.
IsxEve is still a work in progress, but I really appreciate all the time and energy Amadeus and the script writers put into it. Some of their stuff I use "as is", but most I modify (or use as examples when developing my own scripts) to suit my particular style of play.
To me, MMO games are more fun because of what projects like IsxEve allow me to do in the game. I have fun writing scripts and macros, and trying different things out -- and that keeps my interest in a game longer than it otherwise would. I probably would have quit Eve by now, if it weren't for IsxEve.